TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer

Lung cancer remains a disease of high mortality, despite advanced diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in lung neoplasms. Our immunohistochemistry (IHC) studies have shown that high MUC4 expression correlates with a poor outcome. We have also sh...

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Detalles Bibliográficos
Autores principales: Yokoyama, Seiya, Higashi, Michiyo, Tsutsumida, Hideaki, Wakimoto, Jouji, Hamada, Tomofumi, Wiest, Edwin, Matsuo, Kei, Kitazono, Ikumi, Goto, Yuko, Guo, Xin, Hamada, Taiji, Yamada, Sohsuke, Hiraki, Tsubasa, Yonezawa, Suguru, Batra, Surinder K., Hollingsworth, Michael A., Tanimoto, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489649/
https://www.ncbi.nlm.nih.gov/pubmed/28680536
http://dx.doi.org/10.18632/genesandcancer.139

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