Cargando…

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Long noncoding RNAs (lncRNAs) have been implicated in hypoxia/HIF-1-associated cancer progression through largely unknown mechanisms. Here we identify MIR31HG as a hypoxia-inducible lncRNA and therefore we name it LncHIFCAR (long noncoding HIF-1α co-activating RNA); we describe its oncogenic role as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shih, Jing-Wen, Chiang, Wei-Fan, Wu, Alexander T. H., Wu, Ming-Heng, Wang, Ling-Yu, Yu, Yen-Ling, Hung, Yu-Wen, Wang, Wen-Chang, Chu, Cheng-Ying, Hung, Chiu-Lien, Changou, Chun A., Yen, Yun, Kung, Hsing-Jien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489688/ https://www.ncbi.nlm.nih.gov/pubmed/28639619 http://dx.doi.org/10.1038/ncomms15874

Ejemplares similares

Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism
por: Shih, Jing-Wen, et al.
Publicado: (2015)

Signaling in and out: long-noncoding RNAs in tumor hypoxia
por: Kuo, Tse-Chun, et al.
Publicado: (2020)

Co-upregulation of miR-31 and its host gene lncRNA MIR31HG in oral squamous cell carcinoma
por: Tu, Hsi-Feng, et al.
Publicado: (2022)

Chromatophagy: Autophagy goes nuclear and captures broken chromatin during arginine-starvation
por: Kung, Hsing-Jien, et al.
Publicado: (2015)

KDM4B as a Target for Prostate Cancer: Structural Analysis and Selective Inhibition by a Novel Inhibitor
por: Chu, Chia-Han, et al.
Publicado: (2014)

Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression
por: Yan, Shaoying, et al.
Publicado: (2018)

Salvia miltiorrhiza Protects Endothelial Dysfunction against Mitochondrial Oxidative Stress
por: Cheng, Yu-Chen, et al.
Publicado: (2021)

Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes
por: Hsu, Sheng-Chieh, et al.
Publicado: (2021)

LncRNA MIR31HG Drives Oncogenicity by Inhibiting the Limb-Bud and Heart Development Gene (LBH) during Oral Carcinoma
por: Chang, Kuo-Wei, et al.
Publicado: (2021)

Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena
por: Shih, Jing-Wen, et al.
Publicado: (2017)

LncRNA MIR31HG targets HIF1A and P21 to facilitate head and neck cancer cell proliferation and tumorigenesis by promoting cell-cycle progression
por: Wang, Ru, et al.
Publicado: (2018)

Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis
por: Hung, Yu-Wen, et al.
Publicado: (2023)

Comparing the Outcomes of Reporting and Trigger Tool Methods to Capture Adverse Events in the Emergency Department
por: Lee, Wen-Huei, et al.
Publicado: (2019)

Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b
por: Yang, H, et al.
Publicado: (2016)

Chinese Herbal Products for Female Infertility in Taiwan: A Population-Based Cohort Study
por: Hung, Yu-Chiang, et al.
Publicado: (2016)

Host gene and its guest: short story about relation of long-noncoding MIR31HG transcript and microRNA miR-31
por: Kolenda, Tomasz, et al.
Publicado: (2023)

Long noncoding RNA MIR31HG abrogates the availability of tumor suppressor microRNA-361 for the growth of osteosarcoma
por: Sun, Yongjie, et al.
Publicado: (2019)

Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation
por: Chen, Tsan-Jan, et al.
Publicado: (2019)

Effective Perturbations of the Amplitude, Gating, and Hysteresis of I(K(DR)) Caused by PT-2385, an HIF-2α Inhibitor
por: Hsiao, Hung-Tsung, et al.
Publicado: (2021)

Pathogenic Hydrogel? A Novel-Entrapment Neuropathy Model Induced by Ultrasound-Guided Perineural Injections
por: Hsiao, Ming-Yen, et al.
Publicado: (2021)

Long noncoding RNA MIR31HG and its splice variants regulate proliferation and migration: prognostic implications for muscle invasive bladder cancer
por: Wu, Sheng, et al.
Publicado: (2020)

Significantly Higher Prevalence Rate of Asthma and Bipolar Disorder Co-Morbidity: A Meta-Analysis and Review Under PRISMA Guidelines
por: Wu, Ming-Kung, et al.
Publicado: (2016)

Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell‐intrinsic properties
por: Eide, Peter W., et al.
Publicado: (2019)

Significantly Higher Peripheral Insulin-Like Growth Factor-1 Levels in Patients With Major Depressive Disorder or Bipolar Disorder Than in Healthy Controls: A Meta-Analysis and Review Under Guideline of PRISMA
por: Tu, Kun-Yu, et al.
Publicado: (2016)

Long Non-Coding RNAs as Functional Codes for Oral Cancer: Translational Potential, Progress and Promises
por: Lei, Cing-Syuan, et al.
Publicado: (2021)

Editorial: Herbal Medicines in Pain Management
por: Hu, Wen-Long, et al.
Publicado: (2022)

Lean Body Mass Predicts Long-Term Survival in Chinese Patients on Peritoneal Dialysis
por: Huang, Jenq-Wen, et al.
Publicado: (2013)

Chinese Herbal Medicine as an Adjunctive Therapy Improves the Survival Rate of Patients with Ischemic Heart Disease: A Nationwide Population-Based Cohort Study
por: Hung, I.-Ling, et al.
Publicado: (2022)

Google Trends-based non-English language query data and epidemic diseases: a cross-sectional study of the popular search behaviour in Taiwan
por: Chang, Yu-Wei, et al.
Publicado: (2020)

Prognostic Significance of O-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer
por: Kuo, Wen-Ling, et al.
Publicado: (2021)

Long, Noncoding RNA SRA Induces Apoptosis of β-Cells by Promoting the IRAK1/LDHA/Lactate Pathway
por: Huang, Yu-Nan, et al.
Publicado: (2021)

Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus
por: Hsieh, Yu-Tung, et al.
Publicado: (2023)

LncRNA MIR31HG controls the proliferation and metastasis of gastric cancer by c-CBL-mediated degradation of β-catenin
por: Peng, Wen, et al.
Publicado: (2023)

MIR31HG, a potential lncRNA in human cancers and non-cancers
por: Ruan, Luxi, et al.
Publicado: (2023)

Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
por: Hung, Chiu-Lien, et al.
Publicado: (2023)

Targeting Tyrosine Kinases and Autophagy in Prostate Cancer
por: Kung, Hsing-Jien
Publicado: (2010)

Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer
por: Wu, Meng-Jen, et al.
Publicado: (2021)

Comparison of Aspergillus-specific antibody cut-offs for the diagnosis of aspergillosis
por: Hsiao, Chien-Wen, et al.
Publicado: (2022)

Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells
por: Chen, Chia-Lin, et al.
Publicado: (2021)

Adjuvant Probiotics of Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 Attenuate Glycemic Levels and Inflammatory Cytokines in Patients With Type 1 Diabetes Mellitus
por: Wang, Chung-Hsing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q924abftgr9sf5p2a3k6susg3r