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Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells
Despite a growing appreciation of γδ T cell contributions to numerous immune responses, the mechanisms that underpin their thymic development remain poorly understood. Here, using precursor/product relationships, we identify thymic stages in two distinct developmental pathways that generate γδ T cel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489697/ https://www.ncbi.nlm.nih.gov/pubmed/28636936 http://dx.doi.org/10.1016/j.celrep.2017.05.071 |