Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells

Despite a growing appreciation of γδ T cell contributions to numerous immune responses, the mechanisms that underpin their thymic development remain poorly understood. Here, using precursor/product relationships, we identify thymic stages in two distinct developmental pathways that generate γδ T cel...

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Detalles Bibliográficos
Autores principales: Sumaria, Nital, Grandjean, Capucine L., Silva-Santos, Bruno, Pennington, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489697/
https://www.ncbi.nlm.nih.gov/pubmed/28636936
http://dx.doi.org/10.1016/j.celrep.2017.05.071

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