Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

BACKGROUND: International consensus recognises four medulloblastoma molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Grp3)), and group 4 (MB(Grp4)), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopatholo...

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Detalles Bibliográficos
Autores principales: Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489698/
https://www.ncbi.nlm.nih.gov/pubmed/28545823
http://dx.doi.org/10.1016/S1470-2045(17)30243-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489698/
https://www.ncbi.nlm.nih.gov/pubmed/28545823
http://dx.doi.org/10.1016/S1470-2045(17)30243-7

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