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A Routine ‘Top-Down’ Approach to Analysis of the Human Serum Proteome
Serum provides a rich source of potential biomarker proteoforms. One of the major obstacles in analysing serum proteomes is detecting lower abundance proteins owing to the presence of hyper-abundant species (e.g., serum albumin and immunoglobulins). Although depletion methods have been used to addre...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489773/ https://www.ncbi.nlm.nih.gov/pubmed/28587287 http://dx.doi.org/10.3390/proteomes5020013 |