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Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain

BACKGROUND: MicroRNAs, small non-coding RNAs, are highly expressed in the mammalian brain, and the dysregulation of microRNA levels may be involved in neurodevelopmental disorders such as autism spectrum disorder (ASD). In the present study, we examined whether prenatal valproic acid (VPA) exposure...

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Detalles Bibliográficos
Autores principales: Hara, Yuta, Ago, Yukio, Takano, Erika, Hasebe, Shigeru, Nakazawa, Takanobu, Hashimoto, Hitoshi, Matsuda, Toshio, Takuma, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490164/
https://www.ncbi.nlm.nih.gov/pubmed/28670439
http://dx.doi.org/10.1186/s13229-017-0149-5