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An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
β-Lactone natural products occur infrequently in nature but possess a variety of potent and valuable biological activities. They are commonly derived from β-hydroxy-α-amino acids, which are themselves valuable chiral building blocks for chemical synthesis and precursors to numerous important medicin...
Autores principales: | Scott, Thomas A., Heine, Daniel, Qin, Zhiwei, Wilkinson, Barrie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490192/ https://www.ncbi.nlm.nih.gov/pubmed/28649989 http://dx.doi.org/10.1038/ncomms15935 |
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