Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression

The serine/threonine kinase LKB1 regulates various cellular processes such as cell proliferation, energy homeostasis and cell polarity and is frequently downregulated in various tumours. Many downstream pathways controlled by LKB1 have been described but little is known about the upstream regulatory...

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Detalles Bibliográficos
Autores principales: Dogliotti, Giada, Kullmann, Lars, Dhumale, Pratibha, Thiele, Christian, Panichkina, Olga, Mendl, Gudrun, Houben, Roland, Haferkamp, Sebastian, Püschel, Andreas W., Krahn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490199/
https://www.ncbi.nlm.nih.gov/pubmed/28649994
http://dx.doi.org/10.1038/ncomms15747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490199/
https://www.ncbi.nlm.nih.gov/pubmed/28649994
http://dx.doi.org/10.1038/ncomms15747

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