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Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice

Neural circuits balance excitatory and inhibitory activity and disruptions in this balance are commonly found in neurodevelopmental disorders. Mice lacking the intellectual disability and autism-associated gene Kirrel3 have an excitation-inhibition imbalance in the hippocampus but the precise synapt...

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Detalles Bibliográficos
Autores principales: Martin, E. Anne, Woodruff, Derek, Rawson, Randi L., Williams, Megan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490256/
https://www.ncbi.nlm.nih.gov/pubmed/28670619
http://dx.doi.org/10.1523/ENEURO.0088-17.2017