Anti-Mycobacterial Evaluation of 7-Chloro-4-Aminoquinolines and Hologram Quantitative Structure–Activity Relationship (HQSAR) Modeling of Amino–Imino Tautomers

In an ongoing research program for the development of new anti-tuberculosis drugs, we synthesized three series (A, B, and C) of 7-chloro-4-aminoquinolines, which were evaluated in vitro against Mycobacterium tuberculosis (MTB). Now, we report the anti-MTB and cytotoxicity evaluations of a new series...

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Detalles Bibliográficos
Autores principales: Bispo, Marcelle L. F., Lima, Camilo H. S., Cardoso, Laura N. F., Candéa, André L. P., Bezerra, Flávio A. F. M., Lourenço, Maria C. S., Henriques, Maria G. M. O., Alencastro, Ricardo B., Kaiser, Carlos R., Souza, Marcus V. N., Albuquerque, Magaly G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490409/
https://www.ncbi.nlm.nih.gov/pubmed/28598408
http://dx.doi.org/10.3390/ph10020052

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