CCR6(+) Th cells in the cerebrospinal fluid of persons with multiple sclerosis are dominated by pathogenic non-classic Th1 cells and GM-CSF-only-secreting Th cells

Considerable attention has been given to CCR6(+) IL-17-secreting CD4(+) T cells (Th17) in the pathology of a number of autoimmune diseases including multiple sclerosis (MS). However, other Th subsets also play important pathogenic roles, including those that secrete IFNγ and GM-CSF. CCR6 expression...

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Detalles Bibliográficos
Autores principales: Restorick, S.M., Durant, L., Kalra, S., Hassan-Smith, G., Rathbone, E., Douglas, M.R., Curnow, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Full-length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490506/
https://www.ncbi.nlm.nih.gov/pubmed/28336414
http://dx.doi.org/10.1016/j.bbi.2017.03.008

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