Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry

Several studies have suggested that free d-Asp has a crucial role in N-methyl d-Asp receptor-mediated neurotransmission playing very important functions in physiological and pathological processes. This paper describes the development of an analytical procedure for the direct and simultaneous determ...

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Detalles Bibliográficos
Autores principales: Fontanarosa, Carolina, Pane, Francesca, Sepe, Nunzio, Pinto, Gabriella, Trifuoggi, Marco, Squillace, Marta, Errico, Francesco, Usiello, Alessandro, Pucci, Piero, Amoresano, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491048/
https://www.ncbi.nlm.nih.gov/pubmed/28662080
http://dx.doi.org/10.1371/journal.pone.0179748

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