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Intratumoural production of TNFα by bacteria mediates cancer therapy
Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacter...
Autores principales: | Murphy, Carola, Rettedal, Elizabeth, Lehouritis, Panos, Devoy, Ciarán, Tangney, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491124/ https://www.ncbi.nlm.nih.gov/pubmed/28662099 http://dx.doi.org/10.1371/journal.pone.0180034 |
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