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Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms

BACKGROUND: Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study i...

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Autores principales: Xue, Zhe, Wang, Fuyu, Sun, Zhenghui, Zhang, Hui, Wu, Chen, Kong, Dongsheng, Xu, Bainan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491137/
https://www.ncbi.nlm.nih.gov/pubmed/28640793
http://dx.doi.org/10.12659/MSM.902225
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author Xue, Zhe
Wang, Fuyu
Sun, Zhenghui
Zhang, Hui
Wu, Chen
Kong, Dongsheng
Xu, Bainan
author_facet Xue, Zhe
Wang, Fuyu
Sun, Zhenghui
Zhang, Hui
Wu, Chen
Kong, Dongsheng
Xu, Bainan
author_sort Xue, Zhe
collection PubMed
description BACKGROUND: Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study investigated the efficacy and clinical application of intraoperative CT in the surgery for giant symptomatic carotid intracavernous aneurysm. MATERIAL/METHODS: A retrospective analysis was performed on 23 cases with giant symptomatic carotid intracavernous aneurysm. BTO testing was performed before surgery. Differential treatments were performed based on the condition of aneurysm, and some patients received intraoperative PCT. Postoperative anti-coagulation was given with DSA or CTA follow-up examinations at 3–6 months, 1 year, and 2 years after surgery. RESULTS: A total of 17 patients received aneurysm isolation coupled with high-flow bypass surgery. Among those, 9 developed early-onset neurological function after surgery, with gradual recover within 6 months. One coma patient died 25 months after discharge. One patient had aneurysm isolation with clapping of anterior communicating artery, and the other 5 cases received artery clapping only. In those patients, 4 had improvement at early phase, while 1 patient had numbness of the oculomotor nerve. Six patients received surgery in the CT room, including 5 cases with single proximal ligation of the internal carotid artery plus 1 aneurysm isolation combined with high-flow bypass surgery. CONCLUSIONS: Intraoperative PCT can provide objective evidence and effective evaluation of cerebral perfusion.
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spelling pubmed-54911372017-07-05 Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms Xue, Zhe Wang, Fuyu Sun, Zhenghui Zhang, Hui Wu, Chen Kong, Dongsheng Xu, Bainan Med Sci Monit Clinical Research BACKGROUND: Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study investigated the efficacy and clinical application of intraoperative CT in the surgery for giant symptomatic carotid intracavernous aneurysm. MATERIAL/METHODS: A retrospective analysis was performed on 23 cases with giant symptomatic carotid intracavernous aneurysm. BTO testing was performed before surgery. Differential treatments were performed based on the condition of aneurysm, and some patients received intraoperative PCT. Postoperative anti-coagulation was given with DSA or CTA follow-up examinations at 3–6 months, 1 year, and 2 years after surgery. RESULTS: A total of 17 patients received aneurysm isolation coupled with high-flow bypass surgery. Among those, 9 developed early-onset neurological function after surgery, with gradual recover within 6 months. One coma patient died 25 months after discharge. One patient had aneurysm isolation with clapping of anterior communicating artery, and the other 5 cases received artery clapping only. In those patients, 4 had improvement at early phase, while 1 patient had numbness of the oculomotor nerve. Six patients received surgery in the CT room, including 5 cases with single proximal ligation of the internal carotid artery plus 1 aneurysm isolation combined with high-flow bypass surgery. CONCLUSIONS: Intraoperative PCT can provide objective evidence and effective evaluation of cerebral perfusion. International Scientific Literature, Inc. 2017-06-22 /pmc/articles/PMC5491137/ /pubmed/28640793 http://dx.doi.org/10.12659/MSM.902225 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Xue, Zhe
Wang, Fuyu
Sun, Zhenghui
Zhang, Hui
Wu, Chen
Kong, Dongsheng
Xu, Bainan
Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title_full Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title_fullStr Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title_full_unstemmed Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title_short Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
title_sort intraoperative computed tomography (ct) for treating giant carotid intracavernous aneurysms
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491137/
https://www.ncbi.nlm.nih.gov/pubmed/28640793
http://dx.doi.org/10.12659/MSM.902225
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