Cargando…
CARMIL family proteins as multidomain regulators of actin-based motility
CARMILs are large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major capper of actin filament barbed ends in cells. CARMILs bind directly to CP and induce a conformational change that allosterically decreases but does not abolish its actin-capping activity...
Autores principales: | Stark, Benjamin C., Lanier, M. Hunter, Cooper, John A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491179/ https://www.ncbi.nlm.nih.gov/pubmed/28663287 http://dx.doi.org/10.1091/mbc.E17-01-0019 |
Ejemplares similares
-
CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation
por: Lanier, M. Hunter, et al.
Publicado: (2015) -
Dual regulation of the actin cytoskeleton by CARMIL-GAP
por: Jung, Goeh, et al.
Publicado: (2022) -
Physiological role of the interaction between CARMIL1 and capping protein
por: Edwards, Marc, et al.
Publicado: (2013) -
Single-filament kinetic studies provide novel insights into regulation of actin-based motility
por: Shekhar, Shashank, et al.
Publicado: (2016) -
A Novel Pathogenic Variant in CARMIL2 (RLTPR) Causing CARMIL2 Deficiency and EBV-Associated Smooth Muscle Tumors
por: Yonkof, Jennifer R., et al.
Publicado: (2020)