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Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress

The heterotrimeric kinase AMPK acts as an energy sensor to coordinate cell metabolism with environmental status in species from yeast through humans. Low intracellular ATP leads to AMPK activation through phosphorylation of the activation loop within the catalytic subunit. Other environmental stress...

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Detalles Bibliográficos
Autores principales: Schutt, Katherine L., Moseley, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491188/
https://www.ncbi.nlm.nih.gov/pubmed/28515144
http://dx.doi.org/10.1091/mbc.E17-04-0235