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Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin
A wide variety of drugs bind to human serum albumin (HSA) at its two principal sites, namely site I and site II. A number of reports indicate that drug binding to these two binding sites are not completely independent, and that interactions between ligands of these two discrete sites can play a role...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491222/ https://www.ncbi.nlm.nih.gov/pubmed/28662200 http://dx.doi.org/10.1371/journal.pone.0180404 |