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Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae

G-quadruplexes (G4) are polymorphic four-stranded structures formed by certain G-rich nucleic acids in vitro, but the sequence and structural features dictating their formation and function in vivo remains uncertain. Here we report a structure-function analysis of the complex hCEB1 G4-forming sequen...

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Detalles Bibliográficos
Autores principales: Piazza, Aurèle, Cui, Xiaojie, Adrian, Michael, Samazan, Frédéric, Heddi, Brahim, Phan, Anh-Tuan, Nicolas, Alain G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491262/
https://www.ncbi.nlm.nih.gov/pubmed/28661396
http://dx.doi.org/10.7554/eLife.26884