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Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed CRISPR2, lacking cas genes. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Hullahalli, Karthik, Rodrigues, Marinelle, Palmer, Kelli L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491264/
https://www.ncbi.nlm.nih.gov/pubmed/28644125
http://dx.doi.org/10.7554/eLife.26664

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