p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes

To protect germ cells from genomic instability, surveillance mechanisms ensure meiosis occurs properly. In mammals, spermatocytes that display recombination defects experience a so-called recombination-dependent arrest at the pachytene stage, which relies on the MRE11 complex—ATM—CHK2 pathway respon...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcet-Ortega, Marina, Pacheco, Sarai, Martínez-Marchal, Ana, Castillo, Helena, Flores, Elsa, Jasin, Maria, Keeney, Scott, Roig, Ignasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491309/
https://www.ncbi.nlm.nih.gov/pubmed/28617799
http://dx.doi.org/10.1371/journal.pgen.1006845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491309/
https://www.ncbi.nlm.nih.gov/pubmed/28617799
http://dx.doi.org/10.1371/journal.pgen.1006845

Ejemplares similares