Cargando…
Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012
We previously reported a significant reduction in the prevalence of human immunodeficiency virus type 1 (HIV) from 2007 to 2012 in people who inject drugs (PWID; 35.9% to 18.5%, p < 0.001) and female sex workers (FSW; 23.1% to 9.8%, p < 0.05), but not in blood donors (BD) or pregnant women, in...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491323/ https://www.ncbi.nlm.nih.gov/pubmed/28662105 http://dx.doi.org/10.1371/journal.pone.0179616 |
_version_ | 1783247119334768640 |
---|---|
author | Ishizaki, Azumi Tran, Vuong Thi Nguyen, Cuong Hung Tanimoto, Tomoaki Hoang, Huyen Thi Thanh Pham, Hung Viet Phan, Chung Thi Thu Bi, Xiuqiong Pham, Thuc Van Ichimura, Hiroshi |
author_facet | Ishizaki, Azumi Tran, Vuong Thi Nguyen, Cuong Hung Tanimoto, Tomoaki Hoang, Huyen Thi Thanh Pham, Hung Viet Phan, Chung Thi Thu Bi, Xiuqiong Pham, Thuc Van Ichimura, Hiroshi |
author_sort | Ishizaki, Azumi |
collection | PubMed |
description | We previously reported a significant reduction in the prevalence of human immunodeficiency virus type 1 (HIV) from 2007 to 2012 in people who inject drugs (PWID; 35.9% to 18.5%, p < 0.001) and female sex workers (FSW; 23.1% to 9.8%, p < 0.05), but not in blood donors (BD) or pregnant women, in Haiphong, Vietnam. Our aim in the present study was to assess trends in the prevalence of infection with hepatitis B and C viruses (HBV and HCV, respectively). We also investigated the coinfection rates of HBV and HCV with HIV in the same groups. Between 2007 and 2012, HBV prevalence was significantly decreased in BD (18.1% vs. 9.0%, p = 0.007) and slightly decreased in FSW (11.0% vs. 3.9%, p = 0.21), but not in PWID (10.7% vs. 11.1%, p = 0.84). HCV prevalence was significantly decreased in PWID (62.1% in 2007 vs. 42.7% in 2008, p < 0.0001), but it had rebounded to 58.4% in 2012 (2008 vs. 2012, p < 0.0001). HCV prevalence also increased in FSW: 28.6% in 2007 and 2009 vs. 35.3% in 2012; however, this difference was not significant (2007 vs. 2012, p = 0.41). Rates of coinfection with HBV and HCV among HIV-infected PWID and FSW did not change significantly during the study period. Our findings suggest that the current harm reduction programs designed to prevent HIV transmission in PWID and FSW may be insufficient to prevent the transmission of hepatitis viruses, particularly HCV, in Haiphong, Vietnam. New approaches, such as the introduction of catch-up HBV vaccination to vulnerable adult populations and the introduction of HCV treatment as prevention, should be considered to reduce morbidity and mortality due to HIV and hepatitis virus coinfection in Vietnam. |
format | Online Article Text |
id | pubmed-5491323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-54913232017-07-18 Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 Ishizaki, Azumi Tran, Vuong Thi Nguyen, Cuong Hung Tanimoto, Tomoaki Hoang, Huyen Thi Thanh Pham, Hung Viet Phan, Chung Thi Thu Bi, Xiuqiong Pham, Thuc Van Ichimura, Hiroshi PLoS One Research Article We previously reported a significant reduction in the prevalence of human immunodeficiency virus type 1 (HIV) from 2007 to 2012 in people who inject drugs (PWID; 35.9% to 18.5%, p < 0.001) and female sex workers (FSW; 23.1% to 9.8%, p < 0.05), but not in blood donors (BD) or pregnant women, in Haiphong, Vietnam. Our aim in the present study was to assess trends in the prevalence of infection with hepatitis B and C viruses (HBV and HCV, respectively). We also investigated the coinfection rates of HBV and HCV with HIV in the same groups. Between 2007 and 2012, HBV prevalence was significantly decreased in BD (18.1% vs. 9.0%, p = 0.007) and slightly decreased in FSW (11.0% vs. 3.9%, p = 0.21), but not in PWID (10.7% vs. 11.1%, p = 0.84). HCV prevalence was significantly decreased in PWID (62.1% in 2007 vs. 42.7% in 2008, p < 0.0001), but it had rebounded to 58.4% in 2012 (2008 vs. 2012, p < 0.0001). HCV prevalence also increased in FSW: 28.6% in 2007 and 2009 vs. 35.3% in 2012; however, this difference was not significant (2007 vs. 2012, p = 0.41). Rates of coinfection with HBV and HCV among HIV-infected PWID and FSW did not change significantly during the study period. Our findings suggest that the current harm reduction programs designed to prevent HIV transmission in PWID and FSW may be insufficient to prevent the transmission of hepatitis viruses, particularly HCV, in Haiphong, Vietnam. New approaches, such as the introduction of catch-up HBV vaccination to vulnerable adult populations and the introduction of HCV treatment as prevention, should be considered to reduce morbidity and mortality due to HIV and hepatitis virus coinfection in Vietnam. Public Library of Science 2017-06-29 /pmc/articles/PMC5491323/ /pubmed/28662105 http://dx.doi.org/10.1371/journal.pone.0179616 Text en © 2017 Ishizaki et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ishizaki, Azumi Tran, Vuong Thi Nguyen, Cuong Hung Tanimoto, Tomoaki Hoang, Huyen Thi Thanh Pham, Hung Viet Phan, Chung Thi Thu Bi, Xiuqiong Pham, Thuc Van Ichimura, Hiroshi Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title | Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title_full | Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title_fullStr | Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title_full_unstemmed | Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title_short | Discrepancies in prevalence trends for HIV, hepatitis B virus, and hepatitis C virus in Haiphong, Vietnam from 2007 to 2012 |
title_sort | discrepancies in prevalence trends for hiv, hepatitis b virus, and hepatitis c virus in haiphong, vietnam from 2007 to 2012 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491323/ https://www.ncbi.nlm.nih.gov/pubmed/28662105 http://dx.doi.org/10.1371/journal.pone.0179616 |
work_keys_str_mv | AT ishizakiazumi discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT tranvuongthi discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT nguyencuonghung discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT tanimototomoaki discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT hoanghuyenthithanh discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT phamhungviet discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT phanchungthithu discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT bixiuqiong discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT phamthucvan discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 AT ichimurahiroshi discrepanciesinprevalencetrendsforhivhepatitisbvirusandhepatitiscvirusinhaiphongvietnamfrom2007to2012 |