Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus

Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. The patient's sputum gr...

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Detalles Bibliográficos
Autores principales: Moazam, Samihah, Denning, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491460/
https://www.ncbi.nlm.nih.gov/pubmed/28702318
http://dx.doi.org/10.1016/j.mmcr.2017.06.004
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author Moazam, Samihah
Denning, David W.
author_facet Moazam, Samihah
Denning, David W.
author_sort Moazam, Samihah
collection PubMed
description Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. The patient's sputum grew Aspergillus ochraceus thrice over 6 months, alongside positive Aspergillus IgG and serum galactomannan. Despite treatment with itraconazole, the patient continued to be symptomatic. We present the first case associating A. ochraceus with chronic pulmonary aspergillosis.
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spelling pubmed-54914602017-07-12 Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus Moazam, Samihah Denning, David W. Med Mycol Case Rep Case Report Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. The patient's sputum grew Aspergillus ochraceus thrice over 6 months, alongside positive Aspergillus IgG and serum galactomannan. Despite treatment with itraconazole, the patient continued to be symptomatic. We present the first case associating A. ochraceus with chronic pulmonary aspergillosis. Elsevier 2017-06-21 /pmc/articles/PMC5491460/ /pubmed/28702318 http://dx.doi.org/10.1016/j.mmcr.2017.06.004 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Moazam, Samihah
Denning, David W.
Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title_full Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title_fullStr Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title_full_unstemmed Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title_short Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
title_sort aspergillus nodules in chronic granulomatous disease attributable to aspergillus ochraceus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491460/
https://www.ncbi.nlm.nih.gov/pubmed/28702318
http://dx.doi.org/10.1016/j.mmcr.2017.06.004
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