No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice

Base excision repair (BER) is a major pathway for removal of DNA base lesions and maintenance of genomic stability, which is essential in cancer prevention. DNA glycosylases recognize and remove specific lesions in the first step of BER. The existence of a number of these enzymes with overlapping su...

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Detalles Bibliográficos
Autores principales: Rolseth, Veslemøy, Luna, Luisa, Olsen, Ann Karin, Suganthan, Rajikala, Scheffler, Katja, Neurauter, Christine G., Esbensen, Ying, Kuśnierczyk, Anna, Hildrestrand, Gunn A., Graupner, Anne, Andersen, Jill M., Slupphaug, Geir, Klungland, Arne, Nilsen, Hilde, Bjørås, Magnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491499/
https://www.ncbi.nlm.nih.gov/pubmed/28663564
http://dx.doi.org/10.1038/s41598-017-04472-4

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