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Desensitized D2 autoreceptors are resistant to trafficking
Dendritic release of dopamine activates dopamine D2 autoreceptors, which are inhibitory G protein-coupled receptors (GPCRs), to decrease the excitability of dopamine neurons. This study used tagged D2 receptors to identify the localization and distribution of these receptors in living midbrain dopam...
Autores principales: | Robinson, Brooks G., Bunzow, James R., Grimm, Jonathan B., Lavis, Luke D., Dudman, Joshua T., Brown, Jennifer, Neve, Kim A., Williams, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491503/ https://www.ncbi.nlm.nih.gov/pubmed/28663556 http://dx.doi.org/10.1038/s41598-017-04728-z |
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