A Perspective on Reagent Diversity and Non-covalent Binding of Reactive Carbonyl Species (RCS) and Effector Reagents in Non-enzymatic Glycation (NEG): Mechanistic Considerations and Implications for Future Research

This perspective focuses on illustrating the underappreciated connections between reactive carbonyl species (RCS), initial binding in the nonenzymatic glycation (NEG) process, and nonenzymatic covalent protein modification (here termed NECPM). While glucose is the central species involved in NEG, re...

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Detalles Bibliográficos
Autores principales: Rodnick, Kenneth J., Holman, R. W., Ropski, Pamela S., Huang, Mingdong, Swislocki, Arthur L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491550/
https://www.ncbi.nlm.nih.gov/pubmed/28713809
http://dx.doi.org/10.3389/fchem.2017.00039

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