UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients

INTRODUCTION: UDP-glucuronosyltransferase (UGT) and sulfotransferase (SULT) enzymes are involved in removing sex hormones from circulation. Polymorphic variation in five UGT and SULT genes – UGT1A1 ((TA)(6)/(TA)(7)), UGT2B4 (Asp(458)Glu), UGT2B7 (His(268)Tyr), UGT2B15 (Asp(85)Tyr), and SULT1A1 (Arg(...

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Detalles Bibliográficos
Autores principales: Sparks, Rachel, Ulrich, Cornelia M, Bigler, Jeannette, Tworoger, Shelley S, Yasui, Yutaka, Rajan, Kumar B, Porter, Peggy, Stanczyk, Frank Z, Ballard-Barbash, Rachel, Yuan, Xiaopu, Lin, Ming Gang, McVarish, Lynda, Aiello, Erin J, McTiernan, Anne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549165/
https://www.ncbi.nlm.nih.gov/pubmed/15318931
http://dx.doi.org/10.1186/bcr818

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