Synthesis and cytotoxic activities of novel 4-methoxy-substituted and 5-methyl-substituted (3′S,4′S)-(−)-cis-khellactone derivatives that induce apoptosis via the intrinsic pathway

This study deals with the design and synthesis of a series of novel 4-methoxy-substituted and 5-methyl-substituted (3′S,4′S)-(−)-cis-khellactones. The newly synthesized compounds were characterized by (1)H nuclear magnetic resonance (NMR), (13)C-NMR, mass spectrometry, and elemental analysis. All th...

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Detalles Bibliográficos
Autores principales: Chen, Jingrun, Liu, Junjie, Cui, Dongxiao, Yan, Chaoqun, Meng, Liqiang, Sun, Liqian, Ban, Shurong, Ge, Rui, Liang, Taigang, Li, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491701/
https://www.ncbi.nlm.nih.gov/pubmed/28694689
http://dx.doi.org/10.2147/DDDT.S131753

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