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New targets for therapy in breast cancer: Mammalian target of rapamycin (mTOR) antagonists

Mammalian target of rapamycin (mTOR) is a serine-threonine kinase member of the cellular phosphatidylinositol 3-kinase (PI3K) pathway, which is involved in multiple biologic functions such as transcriptional and translational control. mTOR is a downstream mediator in the PI3K/Akt signaling pathway a...

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Detalles Bibliográficos
Autores principales:	Carraway, Hetty, Hidalgo, Manuel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549184/ https://www.ncbi.nlm.nih.gov/pubmed/15318929 http://dx.doi.org/10.1186/bcr927

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