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15-Deoxy-Delta-12,14-Prostaglandin J(2) Inhibits Lung Inflammation and Remodeling in Distinct Murine Models of Asthma

15-deoxy-Δ-12,14-prostaglandin J(2) (15d-PGJ(2)) has been described as an anti-inflammatory lipid mediator in several in vitro and in vivo studies, but its effect on allergic pulmonary inflammation remains elusive. The aim of this study was to investigate the therapeutic potential of 15d-PGJ(2) base...

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Detalles Bibliográficos
Autores principales: Coutinho, Diego S., Anjos-Valotta, Edna A., do Nascimento, Caio V. M. F., Pires, Ana Lucia A., Napimoga, Marcelo H., Carvalho, Vinícius F., Torres, Rafael C., e Silva, Patrícia M. R., Martins, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491902/
https://www.ncbi.nlm.nih.gov/pubmed/28713373
http://dx.doi.org/10.3389/fimmu.2017.00740