Cargando…
In vitro and in vivo anticancer studies of 2'-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by HDAC inhibition and cell cycle arrest
Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2ʹ-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective c...
Autores principales: | Pande, Aditya Narayan, Biswas, Subhankar, Reddy, Neetinkumar D., Jayashree, B.S., Kumar, Nitesh, Rao, C. Mallikarjuna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491917/ https://www.ncbi.nlm.nih.gov/pubmed/28694750 http://dx.doi.org/10.17179/excli2016-643 |
Ejemplares similares
-
Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer
por: Biswas, Subhankar, et al.
Publicado: (2018) -
Selected novel 5'-amino-2'-hydroxy-1, 3-diaryl-2-propen-1-ones arrest cell cycle of HCT-116 in G(0)/G(1 ) phase
por: Simon, Lalitha, et al.
Publicado: (2016) -
Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer
por: Wankhede, Sonal, et al.
Publicado: (2017) -
Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells
por: Nampoothiri, Madhavan, et al.
Publicado: (2014) -
Hydroxy Chalcones and Analogs with Chemopreventive Properties
por: Birsa, Mihail Lucian, et al.
Publicado: (2023)