Cargando…
Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice
BACKGROUND: The pathology of Alzheimer's disease (AD) is comprised of extracellular amyloid plaques, intracellular tau tangles, dystrophic neurites and neurodegeneration. The mechanisms by which these various pathological features arise are under intense investigation. Here, expanding upon pilo...
Autores principales: | Dickey, Chad A, Gordon, Marcia N, Wilcock, Donna M, Herber, Donna L, Freeman, Melissa J, Morgan, Dave |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549198/ https://www.ncbi.nlm.nih.gov/pubmed/15689237 http://dx.doi.org/10.1186/1471-2202-6-7 |
Ejemplares similares
-
Passive immunotherapy against Aβ in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
por: Wilcock, Donna M, et al.
Publicado: (2004) -
Intracranial Injection of AAV Expressing NEP but Not IDE Reduces Amyloid Pathology in APP+PS1 Transgenic Mice
por: Carty, Nikisha, et al.
Publicado: (2013) -
β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice
por: Sudduth, Tiffany L, et al.
Publicado: (2014) -
Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice
por: Weekman, Erica M, et al.
Publicado: (2014) -
Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
por: Carty, Niki C, et al.
Publicado: (2006)