Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters

Here, we present an electrochemical sensor based on gold electrodes modified with calix[4]arene functionalized with carboxypiperidino groups at the upper rim. It has been demonstrated that these groups are involved in a complex formation with dopamine (DA) on the surface of gold electrodes. The supr...

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Autores principales: Kurzątkowska, Katarzyna, Sayin, Serkan, Yilmaz, Mustafa, Radecka, Hanna, Radecki, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492125/
https://www.ncbi.nlm.nih.gov/pubmed/28608815
http://dx.doi.org/10.3390/s17061368
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author Kurzątkowska, Katarzyna
Sayin, Serkan
Yilmaz, Mustafa
Radecka, Hanna
Radecki, Jerzy
author_facet Kurzątkowska, Katarzyna
Sayin, Serkan
Yilmaz, Mustafa
Radecka, Hanna
Radecki, Jerzy
author_sort Kurzątkowska, Katarzyna
collection PubMed
description Here, we present an electrochemical sensor based on gold electrodes modified with calix[4]arene functionalized with carboxypiperidino groups at the upper rim. It has been demonstrated that these groups are involved in a complex formation with dopamine (DA) on the surface of gold electrodes. The supramolecular complex calix[4]arene–DA created on the gold electrode surface has been characterized electrochemically and the measuring conditions have been optimized. The presented sensor displayed a detection limit in the pM range. The DA determination was performed successfully in the presence of ascorbic acid, uric acid and selected neurotransmitters.
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spelling pubmed-54921252017-07-03 Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters Kurzątkowska, Katarzyna Sayin, Serkan Yilmaz, Mustafa Radecka, Hanna Radecki, Jerzy Sensors (Basel) Article Here, we present an electrochemical sensor based on gold electrodes modified with calix[4]arene functionalized with carboxypiperidino groups at the upper rim. It has been demonstrated that these groups are involved in a complex formation with dopamine (DA) on the surface of gold electrodes. The supramolecular complex calix[4]arene–DA created on the gold electrode surface has been characterized electrochemically and the measuring conditions have been optimized. The presented sensor displayed a detection limit in the pM range. The DA determination was performed successfully in the presence of ascorbic acid, uric acid and selected neurotransmitters. MDPI 2017-06-13 /pmc/articles/PMC5492125/ /pubmed/28608815 http://dx.doi.org/10.3390/s17061368 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kurzątkowska, Katarzyna
Sayin, Serkan
Yilmaz, Mustafa
Radecka, Hanna
Radecki, Jerzy
Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title_full Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title_fullStr Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title_full_unstemmed Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title_short Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters
title_sort gold electrodes modified with calix[4]arene for electrochemical determination of dopamine in the presence of selected neurotransmitters
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492125/
https://www.ncbi.nlm.nih.gov/pubmed/28608815
http://dx.doi.org/10.3390/s17061368
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