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Flexible Proteins at the Origin of Life

Almost all modern proteins possess well-defined, relatively rigid scaffolds that provide structural preorganization for desired functions. Such scaffolds require the sufficient length of a polypeptide chain and extensive evolutionary optimization. How ancestral proteins attained functionality, even...

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Detalles Bibliográficos
Autores principales:	Pohorille, Andrew, Wilson, Michael A., Shannon, Gareth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492145/ https://www.ncbi.nlm.nih.gov/pubmed/28587235 http://dx.doi.org/10.3390/life7020023

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