Cargando…
HIV-1 Tat interacts with LIS1 protein
BACKGROUND: HIV-1 Tat activates transcription of HIV-1 viral genes by inducing phosphorylation of the C-terminal domain (CTD) of RNA polymerase II (RNAPII). Tat can also disturb cellular metabolism by inhibiting proliferation of antigen-specific T lymphocytes and by inducing cellular apoptosis. Tat-...
Autores principales: | Epie, Nicolas, Ammosova, Tatyana, Sapir, Tamar, Voloshin, Yaroslav, Lane, William S, Turner, Willie, Reiner, Orly, Nekhai, Sergei |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549217/ https://www.ncbi.nlm.nih.gov/pubmed/15698475 http://dx.doi.org/10.1186/1742-4690-2-6 |
Ejemplares similares
-
Inhibition of PP2A by LIS1 increases HIV-1 gene expression
por: Epie, Nicolas, et al.
Publicado: (2006) -
Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2005) -
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2006) -
HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription
por: Ivanov, Andrey, et al.
Publicado: (2018) -
Targeting Tat–TAR RNA Interaction for HIV-1 Inhibition
por: Alanazi, Awadh, et al.
Publicado: (2021)