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Sitagliptin, An Anti-diabetic Drug, Suppresses Estrogen Deficiency-Induced OsteoporosisIn Vivo and Inhibits RANKL-Induced Osteoclast Formation and Bone Resorption In Vitro
Postmenopausal osteoporosis is a disease characterized by excessive osteoclastic bone resorption. Some anti-diabetic drugs were demonstrated for anti-osteoclastic bone-loss effects. The present study investigated the skeletal effects of chronic administration of sitagliptin, a dipeptidyl peptidase I...
Autores principales: | Wang, Chuandong, Xiao, Fei, Qu, Xinhua, Zhai, Zanjing, Hu, Guoli, Chen, Xiaodong, Zhang, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492451/ https://www.ncbi.nlm.nih.gov/pubmed/28713268 http://dx.doi.org/10.3389/fphar.2017.00407 |
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