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Reciprocal antagonistic regulation of N-myc mRNA by miR-17 and the neuronal-specific RNA-binding protein HuD

Neuroblastoma is a childhood cancer originating from embryonic neural crest cells. Amplification of the proto-oncogene N-myc, seen in ~30% of neuroblastoma tumors, is a marker for poor prognosis. Recently discovered small regulatory RNAs, microRNAs (miRNAs), are implicated in cancers, including neur...

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Detalles Bibliográficos
Autores principales:	Samaraweera, Leleesha, Spengler, Barbara A., Ross, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492688/ https://www.ncbi.nlm.nih.gov/pubmed/28560387 http://dx.doi.org/10.3892/or.2017.5664

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