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Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization

Torsion mechanical waves have the capability to characterize shear stiffness moduli of soft tissue. Under this hypothesis, a computational methodology is proposed to design and optimize a piezoelectrics-based transmitter and receiver to generate and measure the response of torsional ultrasonic waves...

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Detalles Bibliográficos
Autores principales: Melchor, Juan, Muñoz, Rafael, Rus, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492724/
https://www.ncbi.nlm.nih.gov/pubmed/28617353
http://dx.doi.org/10.3390/s17061402
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author Melchor, Juan
Muñoz, Rafael
Rus, Guillermo
author_facet Melchor, Juan
Muñoz, Rafael
Rus, Guillermo
author_sort Melchor, Juan
collection PubMed
description Torsion mechanical waves have the capability to characterize shear stiffness moduli of soft tissue. Under this hypothesis, a computational methodology is proposed to design and optimize a piezoelectrics-based transmitter and receiver to generate and measure the response of torsional ultrasonic waves. The procedure employed is divided into two steps: (i) a finite element method (FEM) is developed to obtain a transmitted and received waveform as well as a resonance frequency of a previous geometry validated with a semi-analytical simplified model and (ii) a probabilistic optimality criteria of the design based on inverse problem from the estimation of robust probability of detection (RPOD) to maximize the detection of the pathology defined in terms of changes of shear stiffness. This study collects different options of design in two separated models, in transmission and contact, respectively. The main contribution of this work describes a framework to establish such as forward, inverse and optimization procedures to choose a set of appropriate parameters of a transducer. This methodological framework may be generalizable for other different applications.
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spelling pubmed-54927242017-07-03 Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization Melchor, Juan Muñoz, Rafael Rus, Guillermo Sensors (Basel) Article Torsion mechanical waves have the capability to characterize shear stiffness moduli of soft tissue. Under this hypothesis, a computational methodology is proposed to design and optimize a piezoelectrics-based transmitter and receiver to generate and measure the response of torsional ultrasonic waves. The procedure employed is divided into two steps: (i) a finite element method (FEM) is developed to obtain a transmitted and received waveform as well as a resonance frequency of a previous geometry validated with a semi-analytical simplified model and (ii) a probabilistic optimality criteria of the design based on inverse problem from the estimation of robust probability of detection (RPOD) to maximize the detection of the pathology defined in terms of changes of shear stiffness. This study collects different options of design in two separated models, in transmission and contact, respectively. The main contribution of this work describes a framework to establish such as forward, inverse and optimization procedures to choose a set of appropriate parameters of a transducer. This methodological framework may be generalizable for other different applications. MDPI 2017-06-15 /pmc/articles/PMC5492724/ /pubmed/28617353 http://dx.doi.org/10.3390/s17061402 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Melchor, Juan
Muñoz, Rafael
Rus, Guillermo
Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title_full Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title_fullStr Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title_full_unstemmed Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title_short Torsional Ultrasound Sensor Optimization for Soft Tissue Characterization
title_sort torsional ultrasound sensor optimization for soft tissue characterization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492724/
https://www.ncbi.nlm.nih.gov/pubmed/28617353
http://dx.doi.org/10.3390/s17061402
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AT munozrafael torsionalultrasoundsensoroptimizationforsofttissuecharacterization
AT rusguillermo torsionalultrasoundsensoroptimizationforsofttissuecharacterization