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Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines

Cell cycle control is a promising target in cancer treatments, and some small-molecule cyclin-dependent kinase (CDK) inhibitors have exhibited clinical effectiveness. However, no biomarkers predictive of efficacy have been developed. Recent studies have revealed that CDK inhibitor (CKI) proteins, su...

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Detalles Bibliográficos
Autores principales:	Okada, Yoshinari, Kato, Shunsuke, Sakamoto, Yasuhiro, Oishi, Takayuki, Ishioka, Chikashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492844/ https://www.ncbi.nlm.nih.gov/pubmed/28560460 http://dx.doi.org/10.3892/or.2017.5684

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