Cell-Size-Dependent Transcription of FLC and Its Antisense Long Non-coding RNA COOLAIR Explain Cell-to-Cell Expression Variation

Single-cell quantification of transcription kinetics and variability promotes a mechanistic understanding of gene regulation. Here, using single-molecule RNA fluorescence in situ hybridization and mathematical modeling, we dissect cellular RNA dynamics for Arabidopsis FLOWERING LOCUS C (FLC). FLC ex...

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Detalles Bibliográficos
Autores principales: Ietswaart, Robert, Rosa, Stefanie, Wu, Zhe, Dean, Caroline, Howard, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493185/
https://www.ncbi.nlm.nih.gov/pubmed/28624615
http://dx.doi.org/10.1016/j.cels.2017.05.010

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