Cargando…
Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy
Breast cancer has emerged as a leading cancer among women in Africa, necessitating improved understanding of its management across the continent. Although previous studies have described regional trends in therapy, this review aims to summarize continent-wide management and focus specifically on sur...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493273/ https://www.ncbi.nlm.nih.gov/pubmed/28717754 http://dx.doi.org/10.1200/JGO.2016.003095 |
_version_ | 1783247474673057792 |
---|---|
author | Sutter, Stephanie A. Slinker, Aaron Balumuka, Deo Darius Mitchell, Katrina B. |
author_facet | Sutter, Stephanie A. Slinker, Aaron Balumuka, Deo Darius Mitchell, Katrina B. |
author_sort | Sutter, Stephanie A. |
collection | PubMed |
description | Breast cancer has emerged as a leading cancer among women in Africa, necessitating improved understanding of its management across the continent. Although previous studies have described regional trends in therapy, this review aims to summarize continent-wide management and focus specifically on surgical interventions. Current literature shows that the rates of surgery, chemotherapy, and radiation therapy vary across different countries and institutions, indicating the need for greater use of standardized cancer treatment guidelines. Surgery, primarily modified radical mastectomy, is the most common form of therapy described. When chemotherapy is offered, the limited availability and cost of treatment lead to high rates of interruption and premature termination of cycles. Few patients have access to radiation or hormonal therapy because these treatments are not available in many countries. Significant delays in seeking treatment are common and contribute to patients presenting with advanced disease. Although limited infrastructure favors surgical management, interventions to improve early detection behavior, provide timely referrals to medical care, and initiate early treatment with access to clinically justified neo-adjuvant and adjuvant therapy are key to improving prognosis. |
format | Online Article Text |
id | pubmed-5493273 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | American Society of Clinical Oncology |
record_format | MEDLINE/PubMed |
spelling | pubmed-54932732017-07-17 Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy Sutter, Stephanie A. Slinker, Aaron Balumuka, Deo Darius Mitchell, Katrina B. J Glob Oncol Review Article Breast cancer has emerged as a leading cancer among women in Africa, necessitating improved understanding of its management across the continent. Although previous studies have described regional trends in therapy, this review aims to summarize continent-wide management and focus specifically on surgical interventions. Current literature shows that the rates of surgery, chemotherapy, and radiation therapy vary across different countries and institutions, indicating the need for greater use of standardized cancer treatment guidelines. Surgery, primarily modified radical mastectomy, is the most common form of therapy described. When chemotherapy is offered, the limited availability and cost of treatment lead to high rates of interruption and premature termination of cycles. Few patients have access to radiation or hormonal therapy because these treatments are not available in many countries. Significant delays in seeking treatment are common and contribute to patients presenting with advanced disease. Although limited infrastructure favors surgical management, interventions to improve early detection behavior, provide timely referrals to medical care, and initiate early treatment with access to clinically justified neo-adjuvant and adjuvant therapy are key to improving prognosis. American Society of Clinical Oncology 2016-07-06 /pmc/articles/PMC5493273/ /pubmed/28717754 http://dx.doi.org/10.1200/JGO.2016.003095 Text en © 2016 by American Society of Clinical Oncology http://creativecommons.org/licenses/by/4.0/ Licensed under the Creative Commons Attribution 4.0 License: http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Review Article Sutter, Stephanie A. Slinker, Aaron Balumuka, Deo Darius Mitchell, Katrina B. Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title | Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title_full | Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title_fullStr | Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title_full_unstemmed | Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title_short | Surgical Management of Breast Cancer in Africa: A Continent-Wide Review of Intervention Practices, Barriers to Care, and Adjuvant Therapy |
title_sort | surgical management of breast cancer in africa: a continent-wide review of intervention practices, barriers to care, and adjuvant therapy |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493273/ https://www.ncbi.nlm.nih.gov/pubmed/28717754 http://dx.doi.org/10.1200/JGO.2016.003095 |
work_keys_str_mv | AT sutterstephaniea surgicalmanagementofbreastcancerinafricaacontinentwidereviewofinterventionpracticesbarrierstocareandadjuvanttherapy AT slinkeraaron surgicalmanagementofbreastcancerinafricaacontinentwidereviewofinterventionpracticesbarrierstocareandadjuvanttherapy AT balumukadeodarius surgicalmanagementofbreastcancerinafricaacontinentwidereviewofinterventionpracticesbarrierstocareandadjuvanttherapy AT mitchellkatrinab surgicalmanagementofbreastcancerinafricaacontinentwidereviewofinterventionpracticesbarrierstocareandadjuvanttherapy |