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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

This study investigates the challenge of comprehensively cataloging the complete human proteome from a single-cell type using mass spectrometry (MS)-based shotgun proteomics. We modify a classical two-dimensional high-resolution reversed-phase peptide fractionation scheme and optimize a protocol tha...

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Detalles Bibliográficos
Autores principales:	Bekker-Jensen, Dorte B., Kelstrup, Christian D., Batth, Tanveer S., Larsen, Sara C., Haldrup, Christa, Bramsen, Jesper B., Sørensen, Karina D., Høyer, Søren, Ørntoft, Torben F., Andersen, Claus L., Nielsen, Michael L., Olsen, Jesper V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493283/ https://www.ncbi.nlm.nih.gov/pubmed/28601559 http://dx.doi.org/10.1016/j.cels.2017.05.009

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