Sodium Iodate Produces a Strain-Dependent Retinal Oxidative Stress Response Measured In Vivo Using QUEST MRI

PURPOSE: We identify noninvasive biomarkers that measure the severity of oxidative stress within retina layers in sodium iodate (SI)-atrophy vulnerable (C57BL/6 [B6]) and SI-atrophy resistant (129S6/SvEvTac [S6]) mice. METHODS: At 24 hours after administering systemic SI to B6 and S6 mice we measure...

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Detalles Bibliográficos
Autores principales: Berkowitz, Bruce A., Podolsky, Robert H., Lenning, Jacob, Khetarpal, Nikita, Tran, Catherine, Wu, Johnny Y., Berri, Ali M., Dernay, Kristin, Shafie-Khorassani, Fatema, Roberts, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493331/
https://www.ncbi.nlm.nih.gov/pubmed/28666279
http://dx.doi.org/10.1167/iovs.17-21850

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