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Sample size determination for a specific region in multiregional clinical trials with multiple co-primary endpoints

Recently, multi-regional clinical trials (MRCTs), which incorporate subjects from many countries/regions around the world under the same protocol, have been widely conducted by many global pharmaceutical companies. The objective of such trials is to accelerate the development process for a drug and...

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Detalles Bibliográficos
Autores principales:	Huang, Wong-Shian, Hung, Hui-Nien, Hamasaki, Toshimitsu, Hsiao, Chin-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493407/ https://www.ncbi.nlm.nih.gov/pubmed/28665972 http://dx.doi.org/10.1371/journal.pone.0180405

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