Cargando…
Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1
Ephexin4, a guanine nucleotide-exchange factor for RhoG, promotes engulfment of apoptotic cells and cancer cell migration in a RhoG-dependent manner, which is synergistically augmented by Elmo1, an Ephexin4-interacting protein. However, the underlying molecular mechanism remains elusive. Here, we re...
Autores principales: | Kim, Kwanhyeong, Lee, Juyeon, Lee, Sang-Ah, Moon, Hyunji, Park, Boyeon, Kim, Deokhwan, Joo, Young-Eun, Park, Daeho |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493634/ https://www.ncbi.nlm.nih.gov/pubmed/28667327 http://dx.doi.org/10.1038/s41598-017-04810-6 |
Ejemplares similares
-
The Intermolecular Interaction of Ephexin4 Leads to Autoinhibition by Impeding Binding of RhoG
por: Kim, Kwanhyeong, et al.
Publicado: (2018) -
Emerging Roles of Ephexins in Physiology and Disease
por: Kim, Kwanhyeong, et al.
Publicado: (2019) -
The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine
por: Lee, Sang-Ah, et al.
Publicado: (2021) -
Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles
por: Min, Chanhyuk, et al.
Publicado: (2020) -
Crbn modulates calcium influx by regulating Orai1 during efferocytosis
por: Moon, Hyunji, et al.
Publicado: (2020)