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Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes

Hepatitis C virus (HCV) infection of hepatocytes promotes liver fibrosis by activation of hepatic stellate cells (HSCs) and excessive deposition of extracellular matrix in liver tissue. Whether or not host factors released from the HCV-infected hepatocytes play role in HSCs activation is unclear. In...

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Detalles Bibliográficos
Autores principales:	Cheng, Ju-Chien, Tseng, Ching-Ping, Liao, Mei-Huei, Peng, Cheng-Yuan, Yu, Jau-Song, Chuang, Po-Heng, Huang, Jing-Tang, Chen, Jeremy J. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493679/ https://www.ncbi.nlm.nih.gov/pubmed/28667290 http://dx.doi.org/10.1038/s41598-017-04259-7

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