Cargando…
Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells
The development of economical optical devices with a reduced footprint foreseeing manipulation, sorting and detection of single cells and other micro particles have been encouraged by cellular biology requirements. Nonetheless, researchers are still ambitious for advances in this field. This paper p...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493682/ https://www.ncbi.nlm.nih.gov/pubmed/28667312 http://dx.doi.org/10.1038/s41598-017-04490-2 |
_version_ | 1783247543073767424 |
---|---|
author | Rodrigues Ribeiro, Rita S. Dahal, Pabitra Guerreiro, Ariel Jorge, Pedro A. S. Viegas, Jaime |
author_facet | Rodrigues Ribeiro, Rita S. Dahal, Pabitra Guerreiro, Ariel Jorge, Pedro A. S. Viegas, Jaime |
author_sort | Rodrigues Ribeiro, Rita S. |
collection | PubMed |
description | The development of economical optical devices with a reduced footprint foreseeing manipulation, sorting and detection of single cells and other micro particles have been encouraged by cellular biology requirements. Nonetheless, researchers are still ambitious for advances in this field. This paper presents Fresnel zone and phase plates fabricated on mode expanded optical fibres for optical trapping. The diffractive structures were fabricated using focused ion beam milling. The zone plates presented in this work have focal distance of ~5 µm, while the focal distance of the phase plates is ~10 µm. The phase plates are implemented in an optical trapping configuration, and 2D manipulation and detection of 8 µm PMMA beads and yeast cells is reported. This enables new applications for optical trapping setups based on diffractive optical elements on optical fibre tips, where feedback systems can be integrated to automatically detect, manipulate and sort cells. |
format | Online Article Text |
id | pubmed-5493682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-54936822017-07-05 Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells Rodrigues Ribeiro, Rita S. Dahal, Pabitra Guerreiro, Ariel Jorge, Pedro A. S. Viegas, Jaime Sci Rep Article The development of economical optical devices with a reduced footprint foreseeing manipulation, sorting and detection of single cells and other micro particles have been encouraged by cellular biology requirements. Nonetheless, researchers are still ambitious for advances in this field. This paper presents Fresnel zone and phase plates fabricated on mode expanded optical fibres for optical trapping. The diffractive structures were fabricated using focused ion beam milling. The zone plates presented in this work have focal distance of ~5 µm, while the focal distance of the phase plates is ~10 µm. The phase plates are implemented in an optical trapping configuration, and 2D manipulation and detection of 8 µm PMMA beads and yeast cells is reported. This enables new applications for optical trapping setups based on diffractive optical elements on optical fibre tips, where feedback systems can be integrated to automatically detect, manipulate and sort cells. Nature Publishing Group UK 2017-06-30 /pmc/articles/PMC5493682/ /pubmed/28667312 http://dx.doi.org/10.1038/s41598-017-04490-2 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Rodrigues Ribeiro, Rita S. Dahal, Pabitra Guerreiro, Ariel Jorge, Pedro A. S. Viegas, Jaime Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title | Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title_full | Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title_fullStr | Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title_full_unstemmed | Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title_short | Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells |
title_sort | fabrication of fresnel plates on optical fibres by fib milling for optical trapping, manipulation and detection of single cells |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493682/ https://www.ncbi.nlm.nih.gov/pubmed/28667312 http://dx.doi.org/10.1038/s41598-017-04490-2 |
work_keys_str_mv | AT rodriguesribeiroritas fabricationoffresnelplatesonopticalfibresbyfibmillingforopticaltrappingmanipulationanddetectionofsinglecells AT dahalpabitra fabricationoffresnelplatesonopticalfibresbyfibmillingforopticaltrappingmanipulationanddetectionofsinglecells AT guerreiroariel fabricationoffresnelplatesonopticalfibresbyfibmillingforopticaltrappingmanipulationanddetectionofsinglecells AT jorgepedroas fabricationoffresnelplatesonopticalfibresbyfibmillingforopticaltrappingmanipulationanddetectionofsinglecells AT viegasjaime fabricationoffresnelplatesonopticalfibresbyfibmillingforopticaltrappingmanipulationanddetectionofsinglecells |