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Validity Examination of the Dissipative Quantum Model of Olfaction

Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative od...

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Detalles Bibliográficos
Autores principales: Tirandaz, Arash, Taher Ghahramani, Farhad, Salari, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493690/
https://www.ncbi.nlm.nih.gov/pubmed/28667321
http://dx.doi.org/10.1038/s41598-017-04846-8
Descripción
Sumario:Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative odorant-mediated inelastic electron tunneling mechanism of olfaction, to be used as a potential examination in experiments. Our analysis gives several predictions on the model such as efficiency of elastic and inelastic tunneling of electrons through odorants, sensitivity thresholds in terms of temperature and pressure, isotopic effect on sensitivity, and the chiral recognition for discrimination between the similar and different scents. Our predictions should yield new knowledge to design new experimental protocols for testing the validity of the model.