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Validity Examination of the Dissipative Quantum Model of Olfaction

Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative od...

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Autores principales: Tirandaz, Arash, Taher Ghahramani, Farhad, Salari, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493690/
https://www.ncbi.nlm.nih.gov/pubmed/28667321
http://dx.doi.org/10.1038/s41598-017-04846-8
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author Tirandaz, Arash
Taher Ghahramani, Farhad
Salari, Vahid
author_facet Tirandaz, Arash
Taher Ghahramani, Farhad
Salari, Vahid
author_sort Tirandaz, Arash
collection PubMed
description Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative odorant-mediated inelastic electron tunneling mechanism of olfaction, to be used as a potential examination in experiments. Our analysis gives several predictions on the model such as efficiency of elastic and inelastic tunneling of electrons through odorants, sensitivity thresholds in terms of temperature and pressure, isotopic effect on sensitivity, and the chiral recognition for discrimination between the similar and different scents. Our predictions should yield new knowledge to design new experimental protocols for testing the validity of the model.
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spelling pubmed-54936902017-07-05 Validity Examination of the Dissipative Quantum Model of Olfaction Tirandaz, Arash Taher Ghahramani, Farhad Salari, Vahid Sci Rep Article Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative odorant-mediated inelastic electron tunneling mechanism of olfaction, to be used as a potential examination in experiments. Our analysis gives several predictions on the model such as efficiency of elastic and inelastic tunneling of electrons through odorants, sensitivity thresholds in terms of temperature and pressure, isotopic effect on sensitivity, and the chiral recognition for discrimination between the similar and different scents. Our predictions should yield new knowledge to design new experimental protocols for testing the validity of the model. Nature Publishing Group UK 2017-06-30 /pmc/articles/PMC5493690/ /pubmed/28667321 http://dx.doi.org/10.1038/s41598-017-04846-8 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tirandaz, Arash
Taher Ghahramani, Farhad
Salari, Vahid
Validity Examination of the Dissipative Quantum Model of Olfaction
title Validity Examination of the Dissipative Quantum Model of Olfaction
title_full Validity Examination of the Dissipative Quantum Model of Olfaction
title_fullStr Validity Examination of the Dissipative Quantum Model of Olfaction
title_full_unstemmed Validity Examination of the Dissipative Quantum Model of Olfaction
title_short Validity Examination of the Dissipative Quantum Model of Olfaction
title_sort validity examination of the dissipative quantum model of olfaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493690/
https://www.ncbi.nlm.nih.gov/pubmed/28667321
http://dx.doi.org/10.1038/s41598-017-04846-8
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