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One-pot Synthesis of 6-Aza-chromone Derivatives Through Cascade Carbonylation-Sonogashira-Cyclization

We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction. By controlling the use of bases, both 6-aza-chromones 5 and 3-(4-oxo-1,4-dihydroquinoline-3-carbonyl)-4H-pyrano[3,2-c]quinolin-4-one...

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Detalles Bibliográficos
Autores principales:	Cheng, Gang, Qi, Yingbei, Zhou, Xiaoqian, Sheng, Rong, Hu, Yong-Zhou, Hu, Youhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493695/ https://www.ncbi.nlm.nih.gov/pubmed/28667287 http://dx.doi.org/10.1038/s41598-017-04693-7

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